Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27621808 | 0.78 | KCNN4 (0.45) | KCNN4KCNA3CYP1A2KMT2APDE4B | |
| SCHEMBL16116242 | 0.74 | KCNN4 (0.42) | KCNN4KCNA3CYP1A2KMT2APDE4B | |
| SCHEMBL2392374 | 0.74 | KCNN4 (0.69) | KCNN4KCNA3CYP1A2KMT2AHSP90AA1 | |
| SCHEMBL27693137 | 0.71 | KCNN4 (0.42) | KCNN4KCNA3CYP1A2KMT2APDE4B | |
| SCHEMBL7219595 | 0.71 | KCNN4 (0.51) | KCNN4KCNA3KMT2AHSP90AA1CYP11B1 | |
| SCHEMBL20609247 | 0.70 | KCNN4 (0.41) | KCNN4KCNA3KMT2APDE4BELANE | |
| SCHEMBL3095800 | 0.70 | LMNA (0.47) | KCNN4KCNA3KMT2APDE4BELANE | |
| SCHEMBL7838433 | 0.67 | TSHR (0.41) | KCNN4KCNA3KMT2AELANEHSP90AA1 | |
| SCHEMBL11143509 | 0.67 | KCNA3 (0.47) | KCNN4KCNA3CYP1A2KMT2ACYP2C9 | |
| SCHEMBL22924802 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239901-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-12-16 | — | — | US | disclosed |