Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.51 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392374 | 0.79 | KCNN4 (0.69) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL28044107 | 0.72 | KCNN4 (0.68) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL11143509 | 0.72 | KCNA3 (0.47) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL2403558 | 0.71 | KCNN4 (0.58) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL20772229 | 0.71 | KCNN4 (0.58) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL11501302 | 0.71 | KCNN4 (0.46) | KCNN4KCNA3CYP11B1CYP11B2KMT2A | |
| SCHEMBL1750941 | 0.71 | KCNN4 (0.58) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL2391892 | 0.71 | KCNN4 (0.58) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL2361042 | 0.71 | KCNN4 (0.67) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL27693137 | 0.70 | KCNN4 (0.42) | KCNN4KCNA3TSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627758-B2 | Ligand including (i) at least two different types of heteroatoms selected from nitrogen, phosphorus, and sulfur, and (ii) at least one of imidazole, pyrazole, and pyridine; transition metal complex for carbonylation to aldehyde | SAN DIEGO STATE UNIVERSITY FOUNDATION | 2003-09-30 | — | — | US | disclosed |
| US-20020115860-A1 | Compositions and methods for hydration of terminal alkynes | SAN DIEGO STATE UNIVERSITY FOUNDATION (US) | 2002-08-22 | — | — | US | disclosed |
| US-6380393-B1 | COMPLEX CONTAINING PYRAZOLE RING | SAN DIEGO STATE UNIVERSITY FOUNDATION | 2002-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115860-A1 | Compositions and methods for hydration of terminal alkynes | CYCS, MYB, POLN | KCNN4 111/4885KCNA3 760/4885CYP11B1 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.