Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 4/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 3/20 | 0.53 |
| ▸ | HRH1 | P35367 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488310 | 0.89 | L3MBTL1 (0.53) | L3MBTL1STSHSD17B3NPC1THRA | |
| SCHEMBL11263173 | 0.81 | NPC1 (0.81) | L3MBTL1STSHSD17B3NPC1THRA | |
| SCHEMBL14977147 | 0.81 | L3MBTL1 (0.62) | L3MBTL1 | |
| SCHEMBL14977512 | 0.81 | L3MBTL1 (0.62) | L3MBTL1 | |
| SCHEMBL8559049 | 0.81 | NPC1 (0.60) | L3MBTL1NPC1PLA2G4B | |
| SCHEMBL8594796 | 0.81 | L3MBTL1 (0.62) | L3MBTL1 | |
| SCHEMBL14977426 | 0.81 | L3MBTL1 (0.62) | L3MBTL1 | |
| SCHEMBL15199293 | 0.80 | L3MBTL1 (0.60) | L3MBTL1STSHSD17B3NPC1THRA | |
| SCHEMBL29052113 | 0.80 | L3MBTL1 (0.64) | L3MBTL1STSHSD17B3NPC1THRA | |
| SCHEMBL19043463 | 0.79 | NPC1 (0.83) | L3MBTL1STSHSD17B3NPC1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233298-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | ORCHIMED SA (CH) | 1980-11-11 | — | — | US | disclosed |
| US-4058552-A | HYPOCHOLESTEROLEMIA, HYPOLIPIDEMIA | ORCHIMED SA (CH) | 1977-11-15 | — | — | US | disclosed |