Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.50 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.50 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.50 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.50 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.50 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977426 | 1.00 | L3MBTL1 (0.62) | L3MBTL1GAACNR1PPARASOAT2 | |
| SCHEMBL14977147 | 1.00 | L3MBTL1 (0.62) | L3MBTL1GAACNR1PPARASOAT2 | |
| SCHEMBL8594796 | 1.00 | L3MBTL1 (0.62) | L3MBTL1GAACNR1PPARASOAT2 | |
| SCHEMBL8594556 | 0.83 | EPHX2 (0.60) | CNR1CNR2 | |
| SCHEMBL11642285 | 0.83 | POLB (0.69) | L3MBTL1GAACNR1HDAC8HDAC3 | |
| SCHEMBL8443095 | 0.83 | POLB (0.69) | L3MBTL1GAACNR1HDAC8HDAC3 | |
| SCHEMBL10652806 | 0.83 | POLB (0.69) | L3MBTL1GAACNR1HDAC8HDAC3 | |
| SCHEMBL8627520 | 0.81 | NPC1 (0.61) | L3MBTL1GAAS1PR1S1PR3 | |
| SCHEMBL11501423 | 0.81 | L3MBTL1 (0.55) | L3MBTL1 | |
| SCHEMBL18259440 | 0.80 | CNR1 (0.68) | L3MBTL1GAACNR1SOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877809-B2 | Compositions and methods for treating macular degeneration | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-11-04 | — | — | US | disclosed |
| EP-2782449-A1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | Anacor Pharmaceuticals, Inc. (US) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013078071-A1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |