Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
| ▸ | CHAT | P28329 | 1/20 | 0.42 |
| ▸ | ATIC | P31939 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501438 | 0.84 | SNCA (0.52) | SNCACHATATICMEN1KMT2A | |
| SCHEMBL11431851 | 0.82 | KCNMA1 (0.53) | SNCAMEN1KMT2AGAAKCNMA1 | |
| SCHEMBL11422144 | 0.80 | KCNMA1 (0.48) | MEN1KMT2AGAAKCNMA1MAPT | |
| SCHEMBL10422834 | 0.79 | CTSB (0.54) | ATICMEN1KMT2ATHRBDNMT1 | |
| SCHEMBL11433946 | 0.78 | KCNMA1 (0.52) | SNCAMEN1KMT2AGAAKCNMA1 | |
| SCHEMBL11424951 | 0.78 | KCNMA1 (0.51) | MEN1KMT2AGAAKCNMA1MAPT | |
| SCHEMBL11431691 | 0.76 | KCNMA1 (0.54) | SNCAMEN1KMT2AGAAKCNMA1 | |
| SCHEMBL11431850 | 0.76 | HPGD (0.62) | MEN1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL11426568 | 0.74 | KCNMA1 (0.54) | MEN1KMT2AGAAKCNMA1MAPT | |
| SCHEMBL5692741 | 0.74 | CTSB (0.54) | ATICMEN1KMT2AGAACTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |