Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | CHAT | P28329 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501439 | 0.84 | SNCA (0.50) | SNCACHATAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL10823414 | 0.79 | SNCA (0.52) | SNCACHATMEN1THRBKMT2A | |
| SCHEMBL11422142 | 0.79 | MAPT (0.52) | MEN1KMT2AHPSESMN1; SMN2ALDH1A1 | |
| SCHEMBL11348600 | 0.78 | SNCA (0.51) | SNCACHATMEN1THRBKMT2A | |
| SCHEMBL10422834 | 0.78 | CTSB (0.54) | MEN1THRBKMT2ADNMT1DNMT3A | |
| SCHEMBL11433945 | 0.78 | HPGD (0.55) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11431850 | 0.77 | HPGD (0.62) | MEN1KMT2AHPSESMN1; SMN2ALDH1A1 | |
| SCHEMBL10823526 | 0.76 | SNCA (0.47) | SNCACHATMEN1THRBKMT2A | |
| SCHEMBL11431851 | 0.75 | KCNMA1 (0.53) | SNCAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11346496 | 0.74 | HPSE (0.47) | SNCACHATMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |