Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28302809 | 0.87 | TAAR1 (0.57) | TAAR1ADRA2CCHRM2ADRA1ARGS12 | |
| SCHEMBL3369733 | 0.87 | TAAR1 (0.47) | TAAR1ADRA2CCHRM2ADRA1ARGS12 | |
| SCHEMBL19494050 | 0.82 | LMNA (0.50) | TAAR1ADRA2CCHRM2ADRA1ARGS12 | |
| SCHEMBL7043126 | 0.81 | AOC3 (0.50) | TAAR1ADRA2CCHRM2ADRA1ARGS12 | |
| SCHEMBL15481758 | 0.81 | TRPA1 (0.53) | TAAR1ADRA2CCHRM2ADRA1ARGS12 | |
| SCHEMBL17892871 | 0.80 | LMNA (0.58) | TAAR1ADRA2CCHRM2ADRA1ARGS12 | |
| SCHEMBL10794618 | 0.80 | LMNA (0.58) | TAAR1ADRA2CCHRM2ADRA1ARGS12 | |
| SCHEMBL111159 | 0.80 | TRPA1 (0.50) | TAAR1ADRA2CCHRM2ADRA1ARGS12 | |
| SCHEMBL18901666 | 0.80 | LMNA (0.58) | TAAR1ADRA2CCHRM2ADRA1ARGS12 | |
| SCHEMBL4107117 | 0.80 | LMNA (0.58) | TAAR1ADRA2CCHRM2ADRA1ARGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156603-A | COMPLEXED WITH A POLYFUNCTIONAL LEWIS BASE | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4147530-A | Reductions of inorganic substrates with chelated sodium hydridoaluminates or hydridoborates | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4088666-A | Reductions with chelated lithium hydridoaluminates or hydridoborates | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-05-09 | — | — | US | disclosed |