Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306258 | 0.92 | POLB (0.56) | ALDH1A1PKMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL11701515 | 0.91 | — | — | |
| SCHEMBL2576487 | 0.91 | ALDH1A1 (0.50) | ALDH1A1PKMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL7137154 | 0.91 | ALDH1A1 (0.50) | ALDH1A1PKMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL1306972 | 0.88 | ALDH1A1 (0.56) | ALDH1A1PKMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL13377043 | 0.87 | ALDH1A1 (0.80) | ALDH1A1PKMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL1100728 | 0.85 | ALDH1A1 (0.52) | ALDH1A1PKMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL13520193 | 0.85 | ALDH1A1 (0.48) | ALDH1A1PKMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL12921487 | 0.85 | ALOX15 (0.62) | ALDH1A1PKMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL4665999 | 0.85 | ALDH1A1 (0.48) | ALDH1A1PKMPOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | disclosed |