Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501597 | 0.94 | KMT2A (0.46) | KMT2APOLBTDP1HSP90AA1RXFP1 | |
| SCHEMBL11501820 | 0.79 | MTNR1A (0.50) | KMT2APOLBMTNR1AMTNR1BMEN1 | |
| SCHEMBL11502077 | 0.77 | ALDH1A1 (0.33) | ALDH1A1NPY1R | |
| SCHEMBL11501651 | 0.74 | MTNR1A (0.48) | KMT2APOLBMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL11501658 | 0.73 | KDM4E (0.33) | ALDH1A1SMN1; SMN2NPY1R | |
| SCHEMBL11668516 | 0.73 | ALDH1A1 (0.45) | KMT2APOLBHDAC3HDAC4HDAC1 | |
| SCHEMBL6985119 | 0.70 | HDAC3 (0.59) | KMT2APOLBTDP1HSP90AA1RXFP1 | |
| SCHEMBL11312309 | 0.70 | MTNR1A (0.81) | KMT2APOLBTDP1HSP90AA1RXFP1 | |
| SCHEMBL11501890 | 0.70 | TDP1 (0.48) | KMT2APOLBTDP1HSP90AA1RXFP1 | |
| SCHEMBL8032200 | 0.68 | EPHX1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163022-A | ANTIPLAQUE AGENTS | COOPER LABORATORIES, INC. (US) | 1979-07-31 | — | — | US | claimed |