Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503551 | 0.80 | KIF11 (0.31) | KIF11 | |
| SCHEMBL4011121 | 0.74 | KIF11 (0.36) | KIF11KCNN4MAPK1POLB | |
| SCHEMBL11561124 | 0.73 | CNR2 (0.35) | KIF11 | |
| SCHEMBL4653328 | 0.72 | KIF11 (0.35) | KIF11 | |
| SCHEMBL11555971 | 0.72 | CSNK1E (0.35) | — | |
| SCHEMBL24649662 | 0.70 | KIF11 (0.33) | KIF11KCNN4MAPK1POLB | |
| SCHEMBL8077580 | 0.69 | KIF11 (0.38) | KIF11KCNN4MAPK1 | |
| SCHEMBL11503528 | 0.69 | CNR2 (0.33) | KIF11 | |
| SCHEMBL11340509 | 0.69 | CNR2 (0.33) | KIF11 | |
| SCHEMBL27739758 | 0.69 | KIF11 (0.41) | KIF11KCNN4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179451-A | HYPOTENSIVE, ANTIULCER, BRONCHODILATOR, ANTICONVULSANTS OR ANTIMICROBIAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4107441-A | HYPOTENSIVE, ANTIULCER, BRONCHODILATORS, ANTIMICROBIAL, ANTICONVULSANTS | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4061672-A | Derivatives of 9-hydroxy-13-trans-prostenoic acid | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-RE29469-E | PROSTAGLANDINS; BRONCHODILATORS, HYPOTENSIVES, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-11-08 | — | — | US | disclosed |
| US-3950406-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-04-13 | — | — | US | disclosed |