SCHEMBL4653328

SCHEMBL4653328

ClCCC(Cl)C(Cl)OC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.35
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544072 0.77 TSHR (0.39) KIF11TSHR
SCHEMBL11503548 0.72 KIF11 (0.33) KIF11
SCHEMBL8077580 0.68 KIF11 (0.38) KIF11TSHR
SCHEMBL3573169 0.65 KIF11 (0.63) KIF11TSHR
SCHEMBL4367368 0.63 MAPK1 (0.42) KIF11TSHR
SCHEMBL9442094 0.62
Phosphine SCHEMBL8595812 0.62 KIF11 (0.54) KIF11TSHR
SCHEMBL4011121 0.62 KIF11 (0.36) KIF11TSHR
SCHEMBL8572359 0.62 TSHR (0.37) KIF11TSHR
SCHEMBL5282316 0.62 KIF11 (0.59) KIF11TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1138699-B1 Prepolymerization catalyst for use in gas phase polymerization of olefins and process for producing the same SUMITOMO CHEMICAL CO (JP) 2008-06-18 EP claimed
EP-0053899-B1 MAGNESIUM CONTAINING SOLID CATALYST CARRIER, A CATALYST AND ITS USE IN POLYMERIZATION OF OLEFINS TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1987-09-02 EP claimed