SCHEMBL458300

SCHEMBL458300

O=C(c1ccccc1)C(Cl)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
LMNA P02545 4/20 0.59
CES2 O00748 2/20 0.59
CES1 P23141 2/20 0.59
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 4/20 0.48
GAA P10253 2/20 0.48
ATM Q13315 2/20 0.48
CYP3A4 P08684 1/20 0.48
NPC1 O15118 1/20 0.48
HSP90AA1 P07900 1/20 0.48
RAB9A P51151 1/20 0.48
HPGD P15428 1/20 0.48
MDM2 Q00987 1/20 0.45
CYP2D6 P10635 1/20 0.44
SRC P12931 1/20 0.44
TSHR P16473 2/20 0.44
DAO P14920 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10946544 0.88 GAA (0.54) TDP1L3MBTL1LMNACES2CES1
SCHEMBL11750758 0.88 LMNA (0.57) TDP1L3MBTL1LMNACES2CES1
SCHEMBL11750676 0.88 CES2 (0.50) TDP1L3MBTL1LMNACES2CES1
SCHEMBL10948973 0.88 CES2 (0.53) TDP1L3MBTL1LMNACES2CES1
SCHEMBL11750814 0.86 KMT2A (0.50) TDP1L3MBTL1LMNACES2CES1
SCHEMBL10397880 0.86 NPC1 (0.50) TDP1L3MBTL1LMNACES2CES1
SCHEMBL11753603 0.86 TDP1 (0.47) TDP1L3MBTL1LMNACES2CES1
SCHEMBL11749522 0.86 LMNA (0.50) TDP1L3MBTL1LMNACES2CES1
SCHEMBL14519367 0.86 MEN1 (0.52) TDP1L3MBTL1LMNACES2CES1
SCHEMBL11757681 0.86 TDP1 (0.47) TDP1L3MBTL1LMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110790905-B Organic two-dimensional material and preparation method thereof 河北工业大学 2021-12-24 CN claimed
CN-113004837-A UV (ultraviolet) curing pressure-sensitive adhesive 深圳力合博汇光敏材料有限公司 2021-06-22 CN claimed
CN-110790905-A Novel organic two-dimensional material and preparation method thereof 河北工业大学 2020-02-14 CN claimed
US-6734221-B1 A PHOTOINITIATED RADICAL GENERATING COMPONENT AND A PHOTOINITIATOR COMPONENT LOCTITE (R&D) LIMITED (IE) 2004-05-11 US claimed
WO-2001018068-A9 RADIATION-CURABLE, CYANOACRYLATE-CONTAINING COMPOSITIONS LOCTITE CORP (US) 2002-10-03 WO claimed
WO-2001018068-A1 RADIATION-CURABLE, CYANOACRYLATE-CONTAINING COMPOSITIONS LOCTITE CORPORATION (US) 2001-03-15 WO claimed
US-5376503-A A photo-crosslinkable blends consisting of an isoolefin, a para-alkylstyrene and a photoinitiator substituted on the alkyl group of para-alkylstyrene monomers; corrosion, solvent resistance EXXON CHEMICAL PATENTS INC. (US) 1994-12-27 US claimed
EP-0563251-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR LITHOGRAPHIC AND CORROSION-RESISTANT COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1993-10-06 EP claimed
EP-0563271-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1993-10-06 EP claimed
WO-1992011322-A2 UV/EB CURABLE BUTYL COPOLYMERS FOR LITHOGRAPHIC AND CORROSION-RESISTANT COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1992-07-09 WO claimed
WO-1992011295-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1992-07-09 WO claimed
US-4025580-A ACYLATION IN PRESENCE OF LEWIS ACID CATALYST; BIODEGRADABLE PACKAGING OWENS-ILLINOIS, INC. (US) 1977-05-24 US claimed
JP-61291531-A None JP disclosed
EP-3755732-B1 KETONE-CONTAINING CONTROLLED RADICAL INITIATORS FOR POLYMERIZATION REACTIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-09-03 EP disclosed
US-20250029468-A1 VEHICLE-CARRIED HAZARDOUS CHEMICAL SAFETY MONITORING SYSTEM THE THIRD RESEARCH INSTITUTE OF MINISTRY OF PUBLIC SECURITY (CN) 2025-01-23 US disclosed
CN-118702878-A Nanoparticle containing suspension conjugated structure and emulsion thereof 河北工业大学 2024-09-27 CN disclosed
US-3947264-A SUBSTITUTED 2,3-DIHYDRO-,4-OXATHIIN PLANT GROWTH STUNTING AGENTS UNIROYAL, INC. (US) 1976-03-30 US disclosed
US-3945833-A CROSSLINKING, PRINTING INKS TOYO INK MANUFACTURING COMPANY, LTD. (JA) 1976-03-23 US disclosed
US-3933840-A ANTIPHLOGISTIC MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-20 US disclosed
US-3932338-A POLYOLEFINS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-01-13 US disclosed