SCHEMBL11504792

SCHEMBL11504792

OCOc1cccc2c1CCc1ccccc1-2

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.37
CES1 P23141 1/20 0.37
ALDH1A1 P00352 3/20 0.37
PNMT P11086 1/20 0.37
ABCB1 P08183 2/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
MAPK14 Q16539 1/20 0.36
SRD5A1 P18405 1/20 0.36
SRD5A2 P31213 1/20 0.36
HTT P42858 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27509803 0.77 S1PR5 (0.47) MAPTMEN1KMT2A
SCHEMBL27509088 0.77 S1PR5 (0.47) MAPTMEN1KMT2A
SCHEMBL29057230 0.77 CES1 (0.37) DYRK1ACES1ALDH1A1PNMTRAB9A
SCHEMBL28679184 0.74 SRC (0.48) CES1ALDH1A1MAPTRAB9ASRD5A1
SCHEMBL11000829 0.74 PNMT (0.47) DYRK1ACES1ALDH1A1PNMTRAB9A
SCHEMBL14604109 0.72 KCNA3 (0.40) CES1ALDH1A1ABCB1MAPTRAB9A
SCHEMBL8068048 0.72 PNMT (0.46) ALDH1A1PNMTRAB9AHTTMEN1
SCHEMBL18617549 0.71 TDP1 (0.46) ALDH1A1MAPTRAB9AHTTSMN1; SMN2
SCHEMBL8459078 0.71 PNMT (0.45) DYRK1ACES1ALDH1A1PNMTRAB9A
SCHEMBL122969 0.71 BCL2L1 (0.50) CES1PNMTMAPTRAB9ASRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4132541-A INHIBITING PLANT GERMINATION AND GROWTH WITH PHENANTHRENE SUBSTITUTED BY CHLORO, HYDROXY, METHOXY AND ACETYL RIKAGAKU KENKYUSHO (JP) 1979-01-02 US disclosed
US-4022842-A PLANT GROWTH REGULATORS RIKAGAKU KENKYUSHO (JA) 1977-05-10 US disclosed
US-3971651-A 9,10-DIHYDROPHENANTHRENES RIKAGAKU KENKYUSHO (JA) 1976-07-27 US disclosed