Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BAD | Q92934 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373551 | 0.88 | BCL2L1 (0.68) | BCL2L1BADMAOBDRD2DRD3 | |
| SCHEMBL58474 | 0.81 | PNMT (0.58) | BCL2L1BADDRD2DRD3PARP1 | |
| SCHEMBL9386807 | 0.80 | AKR1B1 (0.47) | DRD2CES1MIFPNMTNR1H2 | |
| SCHEMBL29414699 | 0.80 | — | — | |
| SCHEMBL150017 | 0.80 | — | — | |
| Dihydrophenanthrene SCHEMBL155991 | 0.76 | CES1 (0.68) | MAOBPARP1CES1SRD5A1SRD5A2 | |
| Dihydrophenanthrene SCHEMBL30297028 | 0.76 | CES1 (0.68) | MAOBPARP1CES1SRD5A1SRD5A2 | |
| Dihydrophenanthrene SCHEMBL29404495 | 0.76 | CES1 (0.68) | MAOBPARP1CES1SRD5A1SRD5A2 | |
| SCHEMBL1276263 | 0.75 | DRD2 (0.56) | BCL2L1BADDRD2DRD3DRD1 | |
| SCHEMBL382855 | 0.75 | PNMT (0.56) | BCL2L1BADDRD2DRD3CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006071674-A2 | ORAL CARE COMPOSITIONS CONTAINING A EUCALYPTUS EXTRACT | COLGATE-PALMOLIVE COMPANY (US) | 2006-07-06 | — | — | WO | claimed |
| US-20060140883-A1 | Oral care compositions containing a eucalyptus extract | COLGATE-PALMOLIVE COMPANY | 2006-06-29 | — | — | US | claimed |
| EP-2424488-B1 | MICROENCAPSULATED COMPOSITIONS AND METHODS FOR TISSUE MINERALIZATION | PREMIER DENTAL PRODUCTS CO (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-3237069-A1 | ORAL CARE COMPOSITIONS | Kiromic, LLC (US) | 2017-11-01 | — | — | EP | disclosed |
| EP-2866774-B1 | HIGH WATER CONTENT ORAL COMPOSITIONS COMPRISING MICROCRYSTALLINE CELLULOSE AND CARBOXYMETHYLCELLULOSE | COLGATE PALMOLIVE CO (US) | 2017-08-09 | — | — | EP | disclosed |
| US-9724541-B2 | Dental cleaning and polishing composition comprising diamond particles | Kao, Lisa Marie (US) | 2017-08-08 | — | — | US | disclosed |
| WO-2016106313-A1 | ORAL CARE COMPOSITIONS | KIROMIC, LLC (US) | 2016-06-30 | — | — | WO | disclosed |
| CN-103408612-B | Luxuriant and rich with fragrance and Dihydrophenanthrene and application thereof | CHENGDU INSTITUTE OF BIOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-12-09 | — | — | CN | disclosed |
| US-20150164769-A1 | High Water Content Oral Compositions Comprising Microcrystalline Cellulose and Carboxymethylcellulose | COLGATE-PALMOLIVE COMPANY (US) | 2015-06-18 | — | — | US | disclosed |
| EP-2866774-A1 | HIGH WATER CONTENT ORAL COMPOSITIONS COMPRISING MICROCRYSTALLINE CELLULOSE AND CARBOXYMETHYLCELLULOSE | Colgate-Palmolive Company (US) | 2015-05-06 | — | — | EP | disclosed |
| US-8889161-B2 | Microencapsulated compositions and methods for tissue mineralization | PREMIER DENTAL PRODUCTS COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| US-5637747-A | Synthesis of 1,2-dioxetanes and intermediates therefor | TROPIX, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| US-5625077-A | 1,2-dioxetanes | TROPIX, INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0582317-A2 | Synthesis of 1,2-dioxetanes and intermediates therefor | TROPIX, INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| US-5177241-A | SYNTHESIS OF 1,2-DIOXETANES AND INTERMEDIATES THEREFOR | APPLIED BIOSYSTEMS, LLC | 1993-01-05 | — | — | US | disclosed |
| US-4956477-A | Synthesis of 1,2-dioxetanes | TROPIX, INC. (US) | 1990-09-11 | — | — | US | disclosed |
| EP-0368946-A1 | 1,2-DIOXETANES. | QUEST SYSTEMS INC (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0368946-A4 | 1,2-DIOXETANES. | QUEST SYSTEMS INC (US) | 1990-05-14 | — | — | EP | disclosed |
| EP-0363128-A2 | Anti-androgen compounds | ARCH DEVELOPMENT CORPORATION (US) | 1990-04-11 | — | — | EP | disclosed |
| WO-1989006226-A1 | SYNTHESIS OF 1,2-DIOXETANES AND INTERMEDIATES THEREFOR | QUEST SYSTEMS, INC. (US) | 1989-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060140883-A1 | Oral care compositions containing a eucalyptus extract | ELANE, MLEC, TAS2R40 | BCL2L1 567/4885BAD 2505/4885MAOB 4629/4885 |
| US-20150164769-A1 | High Water Content Oral Compositions Comprising Microcrystalline Cellulose and Carboxymethylcellulose | SI, COL14A1, COL2A1 | BCL2L1 3447/4885BAD 4211/4885MAOB 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.