Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ROS1 | P08922 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553132 | 0.76 | CSNK1G1 (0.40) | GAAL3MBTL1SMN1; SMN2MAPTPDE3B | |
| SCHEMBL11505467 | 0.75 | NOX1 (0.51) | GAAL3MBTL1TP53SMN1; SMN2MAPT | |
| SCHEMBL7422398 | 0.73 | L3MBTL1 (0.69) | GAATSHRMAPK1L3MBTL1TP53 | |
| SCHEMBL11748044 | 0.72 | PDE3B (0.33) | SMN1; SMN2PDE3BPDE3APOLBBCHE | |
| SCHEMBL29355260 | 0.67 | TP53 (0.54) | GAATSHRMAPK1L3MBTL1TP53 | |
| SCHEMBL17085858 | 0.67 | TP53 (0.54) | GAATSHRMAPK1L3MBTL1TP53 | |
| SCHEMBL23018540 | 0.67 | L3MBTL1 (0.58) | GAATSHRMAPK1L3MBTL1TP53 | |
| SCHEMBL23018613 | 0.67 | L3MBTL1 (0.58) | GAATSHRMAPK1L3MBTL1TP53 | |
| SCHEMBL8892878 | 0.64 | MAPK1 (0.32) | GAATSHRMAPK1MAPTHPGD | |
| SCHEMBL24439558 | 0.63 | NOX1 (0.67) | GAATSHRMAPK1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157444-A | ANTIPSYCHOTIC, NEUROLEPTIC | AMERICAN CYANAMID COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4144235-A | ANTIPSYCHOTIC, NEUROLEPTIC | AMERICAN CYANAMID COMPANY (US) | 1979-03-13 | — | — | US | disclosed |