Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | PYGB | P11216 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149832 | 1.00 | POLA1 (0.35) | POLA1HTTALOX15PTPN1LGALS3 | |
| SCHEMBL1149836 | 1.00 | POLA1 (0.35) | POLA1HTTALOX15PTPN1LGALS3 | |
| SCHEMBL1149830 | 1.00 | POLA1 (0.35) | POLA1HTTALOX15PTPN1LGALS3 | |
| SCHEMBL1150584 | 1.00 | POLA1 (0.35) | POLA1HTTALOX15PTPN1LGALS3 | |
| SCHEMBL3361579 | 0.81 | POLA1 (0.34) | POLA1HTTLMNA | |
| SCHEMBL8946869 | 0.81 | HTT (0.36) | POLA1HTTLMNA | |
| SCHEMBL11333863 | 0.81 | HTT (0.36) | POLA1HTTLMNA | |
| SCHEMBL9418053 | 0.81 | HTT (0.36) | POLA1HTTLMNA | |
| SCHEMBL2127418 | 0.79 | LMNA (0.51) | HTTALOX15LMNA | |
| SCHEMBL15977348 | 0.78 | ALDH1A1 (0.33) | POLA1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893294-B2 | Process for production of trans-2, 2-dimethyl-3-formylcyclopropanecarboxylic acid ester | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-22 | — | — | US | disclosed |
| US-20090314987-A1 | PROCESS FOR PRODUCTION OF TRANS-2, 2-DIMETHYL-3-FORMYLCYCLOPROPANECARBOXYLIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2053037-A1 | PROCESS FOR PRODUCTION OF TRANS-2,2-DIMETHYL- 3-FORMYLCYCLOPROPANE CARBOXYLIC ACID ESTER | Sumitomo Chemical Company, Limited (JP) | 2009-04-29 | — | — | EP | disclosed |