Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358613 | 0.82 | POLA1 (0.32) | POLA1HTTCYP2C19LMNA | |
| SCHEMBL1150190 | 0.82 | LMNA (0.34) | POLA1HTTLMNA | |
| SCHEMBL3361471 | 0.81 | POLA1 (0.31) | POLA1 | |
| SCHEMBL1150587 | 0.81 | POLA1 (0.35) | POLA1HTTLMNA | |
| SCHEMBL1149830 | 0.81 | POLA1 (0.35) | POLA1HTTLMNA | |
| SCHEMBL1149836 | 0.81 | POLA1 (0.35) | POLA1HTTLMNA | |
| SCHEMBL1149832 | 0.81 | POLA1 (0.35) | POLA1HTTLMNA | |
| SCHEMBL10698726 | 0.81 | GBA1 (0.31) | GBA1 | |
| SCHEMBL3383841 | 0.81 | GBA1 (0.31) | GBA1 | |
| SCHEMBL10698724 | 0.81 | GBA1 (0.31) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958533-B | Optically active bisoxazoline compound, asymmetric catalyst, and method for producing optically active cyclopropane compound using same | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2016-02-10 | — | — | CN | disclosed |
| EP-1783111-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2015-04-08 | — | — | EP | disclosed |
| EP-2781522-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUND, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND USING SAID CATALYST | Sumitomo Chemical Company, Limited (JP) | 2014-09-24 | — | — | EP | disclosed |
| CN-103958533-A | Optically active bis-oxazoline compound, asymmetric catalyst, and method for producing optically active cyclopropane compound using same | SUMITOMO CHEMICAL CO | 2014-07-30 | — | — | CN | disclosed |
| CN-1852887-B | Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same | SUMITOMO CO LTD | 2012-08-15 | — | — | CN | disclosed |
| US-7709651-B2 | asymmetriccomplex of copper(I) trifluoromethanesulfonate and 1,1-bis[2-[(4S)-(tert-butyl)-oxazoline]]cyclopropane is added to 3-methyl-2-butenyl acetate and ethyl diazoacetate using dichloroethane solvent to effect reaction to produce ethyl 3,3-dimethyl-2-(acetoxymethyl)cyclopropanecarboxylate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-05-04 | — | — | US | disclosed |
| US-7705165-B2 | Method for producing optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-27 | — | — | US | disclosed |
| US-7671210-B2 | Process for production of optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-02 | — | — | US | disclosed |
| EP-1783130-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-12-30 | — | — | EP | disclosed |
| CN-100569729-C | The method for preparing optically active cyclopropanecarboxylcompound compound | SUMITOMO CHEMICAL CO (JP) | 2009-12-16 | — | — | CN | disclosed |
| CN-100545166-C | The method for preparing optically active cyclopropanecarboxylcompound compound | SUMITOMO CHEMICAL CO (JP) | 2009-09-30 | — | — | CN | disclosed |
| US-20090048450-A1 | Process for production of optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20080027235-A1 | Method for Producing Optically Active Cyclopropanecarboxylate Compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2008-01-31 | — | — | US | disclosed |
| CN-101001826-A | Method for producing optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL CO (JP) | 2007-07-18 | — | — | CN | disclosed |
| CN-1968958-A | Method for producing optically active cyclopropanecarboxylic ester compound | SUMITOMO CHEMICAL CO (JP) | 2007-05-23 | — | — | CN | disclosed |
| EP-1783111-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-05-09 | — | — | EP | disclosed |
| EP-1783130-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-05-09 | — | — | EP | disclosed |
| US-20070032659-A1 | Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-02-08 | — | — | US | disclosed |
| CN-1852887-A | Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same | SUMITOMO CHEMICAL CO (JP) | 2006-10-25 | — | — | CN | disclosed |
| EP-1674445-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND AND ASYMMETRIC COPPER COMPLEX FOR USE IN THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027235-A1 | Method for Producing Optically Active Cyclopropanecarboxylate Compound | ACSL6, AOC1, CA6 | POLA1 2556/4885HTT 4161/4885CYP2C19 1484/4885 |
| US-20090048450-A1 | Process for production of optically active cyclopropanecarboxylate compound | CBR3, C9, CBR1 | POLA1 2124/4885HTT 3681/4885CYP2C19 303/4885 |
| US-20070032659-A1 | Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same | CBR3, AOC3, CBR1 | POLA1 1080/4885HTT 3442/4885CYP2C19 412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.