Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 4/20 | 0.31 |
| ▸ | SI | P14410 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507701 | 1.00 | KDM4E (0.51) | KDM4ELMNACYP2D6CYP2C19MMP9 | |
| SCHEMBL18075995 | 0.83 | KDM4E (0.72) | KDM4ELMNACYP2D6CYP2C19CA2 | |
| SCHEMBL13971011 | 0.82 | KDM4E (0.68) | KDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL21843050 | 0.77 | ALDH1A1 (0.43) | MMP9MMP12CA2CA9CA1 | |
| SCHEMBL26901169 | 0.77 | ALDH1A1 (0.43) | MMP9MMP12CA2CA9CA1 | |
| SCHEMBL11507526 | 0.77 | KDM4E (0.51) | KDM4ELMNACYP2D6CYP2C19MMP9 | |
| SCHEMBL11507529 | 0.77 | KDM4E (0.51) | KDM4ELMNACYP2D6CYP2C19MMP9 | |
| SCHEMBL11882540 | 0.76 | KDM4E (0.40) | KDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL11508250 | 0.75 | CA2 (0.35) | MMP9MMP12CA2CA9CA1 | |
| SCHEMBL11508246 | 0.75 | CA2 (0.35) | MMP9MMP12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180655-A | ANTITUMOR AND ANTILEUKEMIA AGENTS | Suami, Tetsuo (JP) | 1979-12-25 | — | — | US | disclosed |
| US-4086415-A | ANTILEUKEMIA, ANTITUMOR | Suami, Tetsuo (JA) | 1978-04-25 | — | — | US | disclosed |