Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 15/20 | 0.43 |
| ▸ | CASR | P41180 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115176 | 0.86 | KDM4E (0.42) | METAP2CASRBRD4TACR1 | |
| SCHEMBL113668 | 0.84 | CASR (0.38) | CASRBRD4TACR1 | |
| SCHEMBL113670 | 0.82 | CASR (0.38) | CASRBRD4TACR1 | |
| SCHEMBL115108 | 0.82 | METAP2 (0.43) | METAP2 | |
| SCHEMBL115214 | 0.82 | BRD4 (0.42) | CASRBRD4TACR1 | |
| SCHEMBL115047 | 0.80 | METAP2 (0.43) | METAP2BRD4TACR1 | |
| SCHEMBL113625 | 0.77 | METAP2 (0.41) | METAP2CASR | |
| SCHEMBL115974 | 0.76 | METAP2 (0.42) | METAP2 | |
| SCHEMBL116024 | 0.76 | METAP2 (0.39) | METAP2BRD4TACR1 | |
| SCHEMBL114967 | 0.76 | METAP2 (0.39) | METAP2BRD4TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | METAP2 2747/4885CASR 4298/4885BRD4 3524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.