Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11507922 | 0.74 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL28575906 | 0.68 | RAPGEF4 (0.35) | ALDH1A1 | |
| SCHEMBL29378184 | 0.67 | KDM4E (0.37) | ALDH1A1 | |
| SCHEMBL127356 | 0.67 | KDM4E (0.37) | ALDH1A1 | |
| SCHEMBL4867080 | 0.67 | KDM4E (0.37) | ALDH1A1 | |
| Bromide SCHEMBL7236796 | 0.65 | KDM4E (0.36) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11506189 | 0.64 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL11292394 | 0.62 | CYP3A4 (0.48) | ALDH1A1 | |
| SCHEMBL10864783 | 0.62 | ALDH1A1 (0.50) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11507099 | 0.62 | ALDH1A1 (0.56) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136033-A | DIAZO COUPLERS | SANDOZ LTD. (CH) | 1979-01-23 | — | — | US | disclosed |