SCHEMBL11508310

SCHEMBL11508310

O=C(CCCCCCCC(F)(F)F)CC(=O)CCCCCCCC(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 1/20 0.38
FAAH O00519 8/20 0.35
CES1 P23141 5/20 0.35
CES2 O00748 3/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
CYP1A2 P05177 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HDAC6 Q9UBN7 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
MAPT P10636 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
PMP22 Q01453 1/20 0.32
CYSLTR2 Q9NS75 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1648852 0.87 FAAH (0.36) FAAHCES1CES2KMT2AMEN1
SCHEMBL28665298 0.87 HAO1 (0.41) HAO1FAAHCES1CES2KMT2A
SCHEMBL3777069 0.86 KDM4E (0.37) HAO1FAAHKMT2AMAPTLMNA
SCHEMBL6267013 0.82 FAAH (0.42) HAO1FAAHCES1CES2KMT2A
SCHEMBL8999653 0.80 GAA (0.49) HAO1FAAHCES1CES2KMT2A
SCHEMBL25307541 0.79 PLA2G4A (0.33) FAAHCES1CES2KMT2AMEN1
SCHEMBL10309787 0.79 FAAH (0.40) HAO1FAAHCES1CES2KMT2A
SCHEMBL20543468 0.78 FAAH (0.37) FAAHCES1CES2KMT2AMEN1
SCHEMBL5249605 0.78 TSHR (0.60) KMT2AMEN1HSD17B10LMNATSHR
SCHEMBL20543472 0.78 FAAH (0.37) FAAHCES1CES2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4176918-A Fluorescent liquid crystal display TEMPLE UNIVERSITY (US) 1979-12-04 US disclosed