SCHEMBL1648852

SCHEMBL1648852

O=C(CCCCC(F)(F)F)CCCCC(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 1/20 0.36
CES1 P23141 5/20 0.34
CES2 O00748 3/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
HSD17B10 Q99714 1/20 0.34
OXER1 Q8TDS5 1/20 0.34
ALOX5 P09917 1/20 0.33
PLA2G4A P47712 1/20 0.32
LMNA P02545 1/20 0.32
CYSLTR2 Q9NS75 1/20 0.31
CYSLTR1 Q9Y271 1/20 0.31
FOLH1 Q04609 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25307541 0.92 PLA2G4A (0.33) FAAHKMT2AMAPTCES1CES2
SCHEMBL23465661 0.89 HDAC6 (0.35) FAAHKMT2AMAPTMEN1CYP1A2
SCHEMBL11515313 0.89 OXER1 (0.30) FAAHKMT2AMAPTOXER1
SCHEMBL11508310 0.87 HAO1 (0.38) FAAHKMT2AMAPTCES1CES2
SCHEMBL10309787 0.85 FAAH (0.40) FAAHKMT2AMAPTCES1CES2
SCHEMBL3777069 0.84 KDM4E (0.37) FAAHKMT2AMAPTOXER1ALOX5
SCHEMBL6267013 0.84 FAAH (0.42) FAAHKMT2AMAPTCES1CES2
SCHEMBL8744170 0.81 FAAH (0.34) FAAHKMT2ACES1CES2MEN1
SCHEMBL866445 0.81 LMNA (0.58) KMT2AMEN1HSD17B10OXER1ALOX5
SCHEMBL866444 0.81 FAAH (0.34) FAAHKMT2ACES1CES2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109280186-A For solidifying the method and composition on the surface of uncured polysulfide rubber 波音公司 2019-01-29 CN disclosed
WO-2011050245-A1 BICYCLIC HETEROARYLS AS KINASE INHIBITORS FENG YANGBO (US) 2011-04-28 WO disclosed