Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713120 | 0.92 | TDP1 (0.50) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL8496636 | 0.92 | TDP1 (0.50) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL177283 | 0.89 | MAPT (0.41) | KMT2AMAPK1ALDH1A1NPSR1POLB | |
| Isophthalic Acid SCHEMBL3722557 | 0.88 | TDP1 (0.39) | TDP1KMT2AMAPK1HIF1ANPSR1 | |
| SCHEMBL8734973 | 0.87 | RAB9A (0.40) | TDP1KMT2AHIF1AALDH1A1POLB | |
| Ethylene Glycol SCHEMBL2299685 | 0.87 | MAPT (0.39) | KMT2AMAPK1ALDH1A1NPSR1POLB | |
| SCHEMBL11140428 | 0.84 | ALDH1A1 (0.49) | TDP1MAPK1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL9269862 | 0.83 | TDP1 (0.55) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL3978749 | 0.81 | TDP1 (0.41) | TDP1KMT2AMAPK1HIF1ASLC6A2 | |
| SCHEMBL9843596 | 0.80 | PRKCA (0.41) | ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137340-A | Method for fixing electrophoretically formed toner images | AGFA-GEVAERT N.V. (BE) | 1979-01-30 | — | — | US | disclosed |
| US-4130670-A | ELECTROPHORETIC DEPOSITION | AGFA-GEVAERT, N.V. (BE) | 1978-12-19 | — | — | US | disclosed |