Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | TNKS | O95271 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5340573 | 0.80 | TNKS (0.59) | HPGDSMN1; SMN2KDM4EMAPTTNKS | |
| SCHEMBL11511009 | 0.79 | MAOB (0.61) | HPGDSMN1; SMN2KDM4EMAPTTNKS | |
| SCHEMBL4740673 | 0.77 | PPARG (0.50) | HPGDSMN1; SMN2KDM4EMAPTTNKS | |
| SCHEMBL2483048 | 0.77 | KDM4E (0.56) | HPGDSMN1; SMN2KDM4EMAPTTNKS | |
| SCHEMBL30503392 | 0.77 | KDM4E (0.56) | HPGDSMN1; SMN2KDM4EMAPTTNKS | |
| SCHEMBL16915378 | 0.77 | HPGD (0.62) | HPGDSMN1; SMN2KDM4EMAPTTNKS | |
| SCHEMBL28404112 | 0.75 | CYP2C9 (0.50) | HPGDSMN1; SMN2KDM4EMAPTTNKS | |
| SCHEMBL2981579 | 0.75 | NPC1 (0.58) | HPGDSMN1; SMN2KDM4EMAPTTNKS | |
| SCHEMBL11160070 | 0.75 | TNKS (0.50) | HPGDSMN1; SMN2KDM4EMAPTTNKS | |
| SCHEMBL10859564 | 0.74 | CYP2D6 (0.47) | HPGDSMN1; SMN2KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179447-A | ANTIALLERGENS | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4158663-A | FROM 4-METHOXYCOUMARINS USING SODIUM HYDRIDE AND DIMETHYLSULFOXIDE | WARNER-LAMBERT COMPANY (US) | 1979-06-19 | — | — | US | disclosed |