Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508591 | 0.77 | HPGD (0.51) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL28404110 | 0.77 | PPARG (0.52) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL28404112 | 0.73 | CYP2C9 (0.50) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL5340573 | 0.72 | TNKS (0.59) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL22231687 | 0.70 | NPC1 (0.42) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL21510140 | 0.69 | TNKS (0.49) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL30503392 | 0.69 | KDM4E (0.56) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL2483048 | 0.69 | KDM4E (0.56) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL16915378 | 0.69 | HPGD (0.62) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL24310220 | 0.68 | CYP11B1 (0.77) | PPARGKDM4EUSP2CSNK2A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100977-A2 | CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS | N.V. ORGANON (NL) | 2008-08-21 | — | — | WO | disclosed |