Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 8/20 | 0.67 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.67 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.67 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.67 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.67 |
| ▸ | BRD4 | O60885 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.67 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.58 |
| ▸ | GABRP | O00591 | 1/20 | 0.58 |
| ▸ | GABRD | O14764 | 1/20 | 0.58 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507894 | 0.88 | GABRA1 (0.69) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL11507031 | 0.85 | OPRK1 (0.71) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL11508218 | 0.84 | OPRK1 (0.65) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL2973989 | 0.82 | OPRK1 (0.74) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| Alprazolam SCHEMBL5480614 | 0.81 | GABRA1 (1.00) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| Alprazolam SCHEMBL8398 | 0.81 | GABRA1 (1.00) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| Alprazolam SCHEMBL29381667 | 0.81 | GABRA1 (1.00) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| Alprazolam SCHEMBL16922178 | 0.81 | GABRA1 (1.00) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL11809246 | 0.80 | OPRK1 (0.69) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| Alprazolam SCHEMBL22527891 | 0.80 | GABRA1 (0.98) | OPRK1GABRA1GABRA5GABRA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169150-A | MUSCLE RELAXANTS, HYPNOSIS, ANTICONVULSANTS, SEDATIVES | TEIJIN LIMITED (JP) | 1979-09-25 | — | — | US | claimed |
| US-4169150-A | MUSCLE RELAXANTS, HYPNOSIS, ANTICONVULSANTS, SEDATIVES | TEIJIN LIMITED (JP) | 1979-09-25 | — | — | US | disclosed |