Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | DNA2 | P51530 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994834 | 0.79 | ALOX15 (0.59) | KDM4EGAARECQLMAOBALOX15 | |
| SCHEMBL2187863 | 0.71 | SELL (0.48) | KDM4EGAAALOX15GPR35CASP6 | |
| SCHEMBL11509776 | 0.70 | GPR35 (0.66) | MCL1MAOBALOX15ALOX12GPR35 | |
| SCHEMBL11510369 | 0.68 | MAOB (0.59) | MCL1KDM4EGAAMAOBGPR35 | |
| SCHEMBL11508755 | 0.68 | PTPN1 (0.60) | MAOBALOX15CDK2ALDH1A1TDP1 | |
| SCHEMBL9489755 | 0.67 | SELL (0.44) | KDM4EGAAALOX15GPR35CDK2 | |
| SCHEMBL28420685 | 0.67 | ESR1 (0.58) | MCL1GAAALOX15GPR35ESR1 | |
| SCHEMBL7693503 | 0.67 | SELL (0.57) | KDM4EGAAALOX15GPR35CDK2 | |
| SCHEMBL71886 | 0.67 | GPR35 (0.60) | KDM4EALOX15GPR35CASP6CDK2 | |
| SCHEMBL29589123 | 0.67 | GPR35 (0.60) | KDM4EALOX15GPR35CASP6CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159268-A | ANTIBIOTICS, MICROBIOCIDES | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | disclosed |