Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CPT2 | P23786 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27477794 | 0.87 | HMGCR (0.46) | HMGCRCHRM1TBXA2RADRA1AACLY | |
| SCHEMBL11508071 | 0.86 | HMGCR (0.41) | HMGCRCHRM1TBXA2RADRA1AACLY | |
| SCHEMBL10338280 | 0.85 | HMGCR (0.50) | HMGCRCHRM1TBXA2RADRA1AACLY | |
| SCHEMBL9245370 | 0.85 | ACLY (0.46) | HMGCRCHRM1TBXA2RADRA1AACLY | |
| SCHEMBL15243288 | 0.83 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1AACLY | |
| SCHEMBL4948413 | 0.83 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1AACLY | |
| SCHEMBL528207 | 0.81 | ALDH1A1 (0.56) | HMGCRCHRM1TBXA2RADRA1AACLY | |
| SCHEMBL27342657 | 0.78 | ALDH1A1 (0.53) | HMGCRCHRM1TBXA2RADRA1AACLY | |
| SCHEMBL8466961 | 0.77 | ACLY (0.48) | HMGCRCHRM1TBXA2RADRA1AACLY | |
| SCHEMBL960819 | 0.77 | ACLY (0.48) | HMGCRCHRM1TBXA2RADRA1AACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169944-A | CHOLESTEROL BIOSYNTHESIS INHIBITORS | UNIVERSITY PATENTS, INC. (US) | 1979-10-02 | — | — | US | disclosed |