Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511479 | 0.83 | FFAR1 (0.45) | HTR1ASLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL11509887 | 0.83 | HTR1A (0.43) | HTR1ASLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL11508283 | 0.82 | HTR1A (0.43) | HTR1ASLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL24774521 | 0.82 | CHRNA7 (0.44) | HTR1ASLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL11511335 | 0.81 | CHRNB2 (0.49) | CHRNA7KDM1AMCHR2MCHR1CHRNB2 | |
| SCHEMBL11511434 | 0.78 | KDM4E (0.46) | CHRNA7MCHR2MCHR1CHRNB2CHRNB4 | |
| SCHEMBL11509888 | 0.77 | CHRNA7 (0.43) | HTR1ASLC6A2SLC6A4SLC6A3CHRNA7 | |
| SCHEMBL23032150 | 0.75 | CHRNB2 (0.59) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13407277 | 0.75 | CHRNB2 (0.59) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL23423397 | 0.75 | CHRNB2 (0.59) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161529-A | Phenoxy phenyl pyrrolidine compounds, compositions and methods of use | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-07-17 | — | — | US | disclosed |