Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510131 | 0.83 | CHRNB2 (0.42) | PRCPKDM1ACHRNA7 | |
| SCHEMBL11509929 | 0.82 | HTR1A (0.46) | HTR1ASLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL11511479 | 0.80 | FFAR1 (0.45) | HTR1ASLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL11509887 | 0.80 | HTR1A (0.43) | HTR1ASLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL11510979 | 0.80 | PARP14 (0.40) | PRCPDRD2CHRNA7 | |
| SCHEMBL24774521 | 0.73 | CHRNA7 (0.44) | HTR1ASLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL4341158 | 0.73 | PRCP (0.48) | HTR1APRCPDRD2CHRNA7 | |
| SCHEMBL11509888 | 0.71 | CHRNA7 (0.43) | HTR1ASLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL11509371 | 0.71 | OPRM1 (0.43) | — | |
| SCHEMBL11508448 | 0.71 | OPRK1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161529-A | Phenoxy phenyl pyrrolidine compounds, compositions and methods of use | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-07-17 | — | — | US | disclosed |