SCHEMBL11510262

SCHEMBL11510262

CCc1ccccc1OP(=O)(Cl)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.45
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RIPK1 Q13546 1/20 0.40
SRC P12931 1/20 0.40
HPGD P15428 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
HTT P42858 2/20 0.38
ALDH1A1 P00352 1/20 0.37
MAPK8 P45983 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5852162 0.91 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL11792581 0.84 THRA (0.47)
SCHEMBL1958565 0.83 L3MBTL1 (0.47) L3MBTL1MEN1KMT2AMAPTNPSR1
SCHEMBL30039244 0.83 L3MBTL1 (0.47) L3MBTL1MEN1KMT2AMAPTNPSR1
SCHEMBL269292 0.83 L3MBTL1 (0.47) L3MBTL1MEN1KMT2AMAPTNPSR1
SCHEMBL30335093 0.83 L3MBTL1 (0.47) L3MBTL1MEN1KMT2AMAPTNPSR1
Phosphine SCHEMBL27989618 0.81 L3MBTL1 (0.46) L3MBTL1MEN1KMT2AMAPTNPSR1
SCHEMBL11510269 0.81 L3MBTL1 (0.42) L3MBTL1MEN1KMT2AMAPTNPSR1
SCHEMBL11509880 0.80 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL2988651 0.80 SRC (0.48) L3MBTL1MEN1KMT2AMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4144290-A Production of bromoaryl chlorophosphates BAYER AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed