SCHEMBL5852162

SCHEMBL5852162

CCc1ccccc1OP(=O)(Cl)Oc1ccccc1CC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.47
MAPT P10636 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
ATM Q13315 1/20 0.41
HTT P42858 2/20 0.40
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 1/20 0.38
NISCH Q9Y2I1 1/20 0.37
XBP1 P17861 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
GABRA1 P14867 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11510262 0.91 L3MBTL1 (0.45) L3MBTL1MAPTNPSR1HPGDATM
SCHEMBL11509880 0.88 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1SMN1; SMN2LMNA
SCHEMBL11510691 0.87 PPARD (0.40) L3MBTL1MAPTNPSR1SMN1; SMN2LMNA
SCHEMBL5852168 0.85 L3MBTL1 (0.44) L3MBTL1MAPTNPSR1SMN1; SMN2LMNA
SCHEMBL11512732 0.84 THRA (0.44)
SCHEMBL1592230 0.83 L3MBTL1 (0.50) L3MBTL1MAPTNPSR1SMN1; SMN2LMNA
SCHEMBL29636357 0.83 L3MBTL1 (0.50) L3MBTL1MAPTNPSR1SMN1; SMN2LMNA
SCHEMBL778836 0.82 L3MBTL1 (0.48) L3MBTL1MAPTNPSR1SMN1; SMN2LMNA
SCHEMBL11352634 0.81 THRA (0.52)
SCHEMBL21654512 0.81 L3MBTL1 (0.44) L3MBTL1MAPTNPSR1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153901-B2 Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production ALBEMARLE CORPORATION (US) 2006-12-26 US disclosed
EP-1685176-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2006-08-02 EP disclosed
WO-2005052018-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2005-06-09 WO disclosed
US-20050113495-A1 Flame retardant, additive compositions, and flame retardant polyurethanes ALBEMARLE CORPORATION 2005-05-26 US disclosed
US-4144290-A Production of bromoaryl chlorophosphates BAYER AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed