Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11182096 | 0.86 | GAA (0.60) | MEN1KMT2APNMTCA1ACHE | |
| SCHEMBL11511314 | 0.85 | MEN1 (0.68) | MEN1KMT2ASMN1; SMN2RAB9AGFER | |
| SCHEMBL5536759 | 0.82 | PNMT (0.46) | MEN1KMT2APNMTCA1ACHE | |
| SCHEMBL11512742 | 0.82 | KCNJ5 (0.51) | MEN1KMT2APNMTSMN1; SMN2CYP1A2 | |
| SCHEMBL19921027 | 0.82 | CA1 (0.45) | MEN1KMT2APNMTCA1ACHE | |
| SCHEMBL11511999 | 0.80 | ALDH1A1 (0.59) | MEN1KMT2ACA1ACHESMN1; SMN2 | |
| SCHEMBL11887738 | 0.79 | CA1 (0.75) | KMT2ACA1ACHESMN1; SMN2CYP1A2 | |
| SCHEMBL6690806 | 0.78 | RAB9A (0.67) | MEN1KMT2APNMTCA1ACHE | |
| SCHEMBL11510192 | 0.76 | PNMT (0.50) | MEN1KMT2APNMTCYP1A2CYP3A4 | |
| SCHEMBL12682641 | 0.74 | KMT2A (1.00) | MEN1KMT2ASMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |