Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TLR5 | O60602 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509227 | 0.77 | TSHR (0.54) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10011649 | 0.74 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6406195 | 0.73 | KDM4E (0.74) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13832039 | 0.71 | ALDH1A1 (0.62) | KDM4EALDH1A1SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL13831773 | 0.71 | SMN1; SMN2 (0.74) | KDM4EALDH1A1SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL3915525 | 0.71 | ALDH1A1 (0.67) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9402280 | 0.70 | KDM4E (0.70) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6410082 | 0.69 | KMT2A (0.61) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14195584 | 0.69 | TSHR (0.63) | KDM4EALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL3012641 | 0.68 | ALDH1A1 (0.60) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |