Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DNM2 | P50570 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507326 | 1.00 | MMP3 (0.50) | MMP3SMN1; SMN2AKT1TP53POLB | |
| SCHEMBL11509915 | 0.92 | SMN1; SMN2 (0.53) | MMP3SMN1; SMN2AKT1TP53POLB | |
| SCHEMBL10985231 | 0.80 | MMP3 (0.49) | MMP3MAPTKMT2AGSK3BALDH1A1 | |
| SCHEMBL10983494 | 0.80 | MMP3 (0.49) | MMP3MAPTKMT2AGSK3BALDH1A1 | |
| SCHEMBL10982313 | 0.80 | MMP3 (0.49) | MMP3MAPTKMT2AGSK3BALDH1A1 | |
| SCHEMBL7491690 | 0.80 | ALDH1A1 (0.51) | MMP3POLBMAPTGSK3BALDH1A1 | |
| SCHEMBL11664173 | 0.80 | MMP3 (0.46) | MMP3SMN1; SMN2POLBMAPTKMT2A | |
| SCHEMBL10986155 | 0.78 | MMP3 (0.46) | MMP3SMN1; SMN2POLBMAPTKMT2A | |
| SCHEMBL11856640 | 0.76 | MMP3 (0.45) | MMP3SMN1; SMN2AKT1TP53POLB | |
| SCHEMBL11554819 | 0.73 | MMP3 (0.41) | MMP3SMN1; SMN2POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158659-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1979-06-19 | — | — | US | disclosed |
| US-4152442-A | ANTIASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1979-05-01 | — | — | US | disclosed |