Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448617 | 0.85 | ALDH1A1 (0.53) | CISD1GAAGLAHSD17B10ALOX15 | |
| SCHEMBL10900544 | 0.84 | NR4A1 (0.52) | CISD1GAAGLAHSD17B10CYP3A4 | |
| SCHEMBL11028747 | 0.81 | GAA (0.47) | CISD1GAAGLAHSD17B10CYP3A4 | |
| SCHEMBL11353322 | 0.79 | CYP3A4 (0.56) | CISD1GAAGLAHSD17B10CYP3A4 | |
| SCHEMBL6874618 | 0.79 | ALDH1A1 (0.43) | CISD1GAAGLAHSD17B10CYP3A4 | |
| SCHEMBL29835939 | 0.79 | ALDH1A1 (0.43) | CISD1GAAGLAHSD17B10CYP3A4 | |
| SCHEMBL11136116 | 0.78 | GAA (0.45) | CISD1GAAGLAHSD17B10CYP3A4 | |
| SCHEMBL7755552 | 0.77 | GLA (0.44) | CISD1GAAGLAMMP2CA2 | |
| SCHEMBL10799274 | 0.77 | KMT2A (0.52) | GAAGLAHSD17B10CYP3A4ALOX15 | |
| SCHEMBL436522 | 0.74 | NR4A1 (0.61) | GAAMMP2MMP14HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138395-A | Water soluble copper complex monoazo dyestuff based upon ortho-amino phenol-sulfonic acid and N-acetoacetyl compound of amino-benzene-β-hydroxy-ethylsulfone-sulfuric acid ester | AMERICAN HOECHST CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |