Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598685 | 0.89 | PLA2G2A (0.39) | CA2CA1PLA2G2ASMPD1FDPS | |
| SCHEMBL11510134 | 0.89 | CA2 (0.36) | CA2CA1PLA2G2AMAPK1FDPS | |
| SCHEMBL11510893 | 0.78 | CA1 (0.41) | CA2CA1PLA2G2ASMPD1FDPS | |
| SCHEMBL11827440 | 0.77 | MAPT (0.42) | CA2CA1PLA2G2ASMPD1FDPS | |
| SCHEMBL16863974 | 0.76 | CA2 (0.47) | CA2CA1MAPK1ZDHHC7 | |
| SCHEMBL21498901 | 0.74 | CA2 (0.49) | CA2CA1MAPK1ZDHHC7 | |
| SCHEMBL24019741 | 0.73 | CA2 (0.43) | CA2CA1MAPK1ZDHHC7 | |
| SCHEMBL128715 | 0.73 | CA2 (0.54) | CA2CA1MAPK1 | |
| SCHEMBL11187884 | 0.72 | KMT2A (0.41) | — | |
| SCHEMBL11493233 | 0.71 | CA2 (0.53) | CA2CA1MAPK1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144251-A | PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4092427-A | ANTICOAGULANTS, OXYTOCICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |
| US-4048329-A | HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048328-A | HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4007171-A | PROSTAGLANDIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |
| US-3987081-A | ALKYL DERIVATIVES OF PROSTANOIC ACIDS AND PREPARATION THEREOF | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |
| US-3959263-A | Prostaglandin intermediate | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |