Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059694 | 0.91 | TDP1 (0.54) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL11560353 | 0.88 | MEN1 (0.68) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL11371987 | 0.86 | HPGD (0.54) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL12277454 | 0.84 | PDE10A (0.61) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL11513659 | 0.83 | G6PD (0.68) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL11766843 | 0.82 | ALDH1A1 (0.53) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL6029223 | 0.81 | GAA (0.77) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL8092870 | 0.80 | TDP1 (1.00) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| SCHEMBL11509537 | 0.77 | TDP1 (0.42) | TDP1CYP3A4ALDH1A1THRBALOX15 | |
| Methylhydroquinone SCHEMBL537277 | 0.77 | TP53 (0.59) | TDP1CYP3A4ALDH1A1ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4170452-A | Dye composition containing diphenylamine and polyhydroxybenzene | L'OREAL (FR) | 1979-10-09 | — | — | US | disclosed |