SCHEMBL8092870

SCHEMBL8092870

Cc1cc(Nc2ccc(O)cc2)ccc1N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 1.00
CYP3A4 P08684 3/20 1.00
ALDH1A1 P00352 3/20 1.00
THRB P10828 1/20 1.00
ALOX15 P16050 1/20 1.00
RECQL P46063 1/20 1.00
HIF1A Q16665 1/20 1.00
GAA P10253 6/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
G6PD P11413 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
GFER P55789 4/20 0.44
KDM4E B2RXH2 3/20 0.44
MAPT P10636 3/20 0.44
ATM Q13315 1/20 0.44
APP P05067 1/20 0.44
TSHR P16473 3/20 0.43
AURKA O14965 1/20 0.40
DHFR P00374 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11511767 0.88 CYP3A4 (0.77) TDP1CYP3A4ALDH1A1THRBALOX15
SCHEMBL22701365 0.84 ALDH1A1 (0.72) TDP1CYP3A4ALDH1A1THRBALOX15
SCHEMBL29764083 0.84 CYP3A4 (0.71) TDP1CYP3A4ALDH1A1THRBALOX15
SCHEMBL29709 0.84 CYP3A4 (0.71) TDP1CYP3A4ALDH1A1THRBALOX15
SCHEMBL30998047 0.82 ALDH1A1 (0.70) TDP1CYP3A4ALDH1A1THRBALOX15
SCHEMBL2127369 0.82 ALDH1A1 (0.70) TDP1CYP3A4ALDH1A1THRBALOX15
SCHEMBL28255467 0.81 CYP3A4 (0.68) TDP1CYP3A4ALDH1A1THRBALOX15
SCHEMBL11510620 0.80 TDP1 (0.67) TDP1CYP3A4ALDH1A1THRBALOX15
SCHEMBL563875 0.80 CYP3A4 (0.67) TDP1CYP3A4ALDH1A1THRBALOX15
SCHEMBL23999865 0.79 ALDH1A1 (0.66) TDP1CYP3A4ALDH1A1THRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114057916-B Preparation method of lubricating oil antioxidant ashless dispersant 中国石油天然气股份有限公司 2023-11-28 CN claimed
CN-112625777-B Preparation method of lubricating oil antiwear dispersant 中国石油天然气股份有限公司 2022-08-30 CN claimed
CN-114057916-A Preparation method of antioxidant ashless dispersant for lubricating oil 中国石油天然气股份有限公司 2022-02-18 CN claimed
CN-112625777-A Preparation method of lubricating oil antiwear dispersant 中国石油天然气股份有限公司 2021-04-09 CN claimed
US-4870049-A TRANSFER SHEET FOR THERMAL PRINTING SHARP KABUSHIKI KAISHA (JP) 1989-09-26 US claimed
CN-114057916-B Preparation method of lubricating oil antioxidant ashless dispersant 中国石油天然气股份有限公司 2023-11-28 CN disclosed
CN-112423862-B Hydrogen sulfide removal process by using sulfur dye catalyst 摩瑞奇曼公司 2023-04-18 CN disclosed
CN-112625777-B Preparation method of lubricating oil antiwear dispersant 中国石油天然气股份有限公司 2022-08-30 CN disclosed
WO-2022142063-A1 METHOD FOR TRANSFER DYEING OF DENIM USING SUSPENSION DYE 长胜纺织科技发展(上海)有限公司 2022-07-07 WO disclosed
CN-114057916-A Preparation method of antioxidant ashless dispersant for lubricating oil 中国石油天然气股份有限公司 2022-02-18 CN disclosed
CN-112625777-A Preparation method of lubricating oil antiwear dispersant 中国石油天然气股份有限公司 2021-04-09 CN disclosed
EP-0750490-B1 ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES HENKEL KGAA (DE) 2000-11-08 EP disclosed
EP-0695163-B1 ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES HENKEL KGAA (DE) 1997-03-05 EP disclosed
EP-0695163-A1 ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES HENKEL KGAA (DE) 1996-02-07 EP disclosed
WO-1995011001-A1 1,3-PROPANDIONES FOR DYEING KERATINIC FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1995-04-27 WO disclosed
WO-1994024989-A1 ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-11-10 WO disclosed
US-4870049-A TRANSFER SHEET FOR THERMAL PRINTING SHARP KABUSHIKI KAISHA (JP) 1989-09-26 US disclosed