Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.63 |
| ▸ | PGR | P06401 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | MLNR | O43193 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 3/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510778 | 1.00 | LMNA (0.63) | LMNACYP3A4NR3C1PGRSMN1; SMN2 | |
| SCHEMBL11511941 | 0.91 | LMNA (0.65) | LMNACYP3A4NR3C1PGRSMN1; SMN2 | |
| SCHEMBL11511949 | 0.91 | LMNA (0.65) | LMNACYP3A4NR3C1PGRSMN1; SMN2 | |
| SCHEMBL11511438 | 0.89 | LMNA (0.78) | LMNACYP3A4NR3C1PGRSMN1; SMN2 | |
| SCHEMBL11511435 | 0.89 | LMNA (0.78) | LMNACYP3A4NR3C1PGRSMN1; SMN2 | |
| SCHEMBL3973882 | 0.84 | LMNA (0.75) | LMNACYP3A4NR3C1PGRSMN1; SMN2 | |
| SCHEMBL11515560 | 0.82 | NR3C1 (0.86) | LMNACYP3A4NR3C1PGRSMN1; SMN2 | |
| Haloprogesterone SCHEMBL139522 | 0.80 | AR (0.64) | LMNACYP3A4NR3C1PGRSMN1; SMN2 | |
| Haloprogesterone SCHEMBL139523 | 0.80 | AR (0.64) | LMNACYP3A4NR3C1PGRSMN1; SMN2 | |
| SCHEMBL22749094 | 0.79 | LMNA (0.77) | LMNACYP3A4NR3C1PGRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177269-A | ANTITUMOR AGENTS | AKTIEBOLAGET LEO (SE) | 1979-12-04 | — | — | US | disclosed |