Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512682 | 0.87 | KMT2A (0.50) | SMN1; SMN2HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11509397 | 0.84 | ALDH1A1 (0.52) | SMN1; SMN2HTTNPC1RAB9AKMT2A | |
| SCHEMBL11509941 | 0.75 | MAPT (0.37) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11512125 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2HTTNPC1RAB9AKMT2A | |
| SCHEMBL11512018 | 0.68 | NPC1 (0.54) | SMN1; SMN2HTTNPC1RAB9AKMT2A | |
| SCHEMBL9745598 | 0.68 | HPGD (0.53) | SMN1; SMN2HTTNPC1RAB9AKMT2A | |
| SCHEMBL9491957 | 0.68 | HPGD (0.53) | SMN1; SMN2HTTNPC1RAB9AKMT2A | |
| SCHEMBL6304397 | 0.68 | HPGD (0.53) | SMN1; SMN2HTTNPC1RAB9AKMT2A | |
| SCHEMBL5316777 | 0.68 | HPGD (0.53) | SMN1; SMN2HTTNPC1RAB9AKMT2A | |
| SCHEMBL11953074 | 0.67 | ALDH1A1 (0.50) | SMN1; SMN2HTTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |