Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510982 | 0.87 | SMN1; SMN2 (0.50) | KMT2AALDH1A1MAPTGAAHPGD | |
| SCHEMBL11509397 | 0.83 | ALDH1A1 (0.52) | KMT2AALDH1A1MAPTGAAHPGD | |
| SCHEMBL11512125 | 0.75 | ALDH1A1 (0.48) | KMT2AALDH1A1MAPTGAAHPGD | |
| SCHEMBL17761121 | 0.74 | ALDH1A1 (0.68) | KMT2AALDH1A1MAPTHPGDLMNA | |
| SCHEMBL24305911 | 0.74 | ALDH1A1 (0.68) | KMT2AALDH1A1MAPTHPGDLMNA | |
| SCHEMBL11509941 | 0.73 | MAPT (0.37) | KMT2AALDH1A1MAPTGAAHPGD | |
| SCHEMBL11511738 | 0.73 | KMT2A (0.48) | KMT2AALDH1A1MAPTGAAHPGD | |
| SCHEMBL16526226 | 0.72 | ALDH1A1 (0.70) | KMT2AALDH1A1MAPTHPGDLMNA | |
| SCHEMBL11512132 | 0.71 | DRD2 (0.78) | KMT2AALDH1A1MAPTGAAHPGD | |
| SCHEMBL11512018 | 0.69 | NPC1 (0.54) | KMT2AALDH1A1MAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |