Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.78 |
| ▸ | PGR | P06401 | 4/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.78 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | MLNR | O43193 | 1/20 | 0.78 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.78 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.78 |
| ▸ | AR | P10275 | 2/20 | 0.76 |
| ▸ | SHBG | P04278 | 5/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801424 | 0.92 | AR (0.82) | LMNASMN1; SMN2NR3C1CYP3A4PGR | |
| SCHEMBL571389 | 0.91 | LMNA (0.77) | LMNASMN1; SMN2NR3C1CYP3A4PGR | |
| SCHEMBL11510015 | 0.91 | LMNA (0.77) | LMNASMN1; SMN2NR3C1CYP3A4PGR | |
| SCHEMBL11510625 | 0.91 | LMNA (0.77) | LMNASMN1; SMN2NR3C1CYP3A4PGR | |
| SCHEMBL11513688 | 0.91 | LMNA (0.85) | LMNASMN1; SMN2NR3C1CYP3A4PGR | |
| SCHEMBL20101055 | 0.90 | NR3C1 (0.88) | LMNASMN1; SMN2NR3C1CYP3A4PGR | |
| SCHEMBL260024 | 0.90 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2NR3C1CYP3A4PGR | |
| SCHEMBL29766827 | 0.90 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2NR3C1CYP3A4PGR | |
| SCHEMBL13941349 | 0.90 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2NR3C1CYP3A4PGR | |
| SCHEMBL27048175 | 0.90 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2NR3C1CYP3A4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177269-A | ANTITUMOR AGENTS | AKTIEBOLAGET LEO (SE) | 1979-12-04 | — | — | US | disclosed |