Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.88 |
| ▸ | LMNA | P02545 | 6/20 | 0.88 |
| ▸ | PGR | P06401 | 5/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.88 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.88 |
| ▸ | MEN1 | O00255 | 2/20 | 0.88 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.88 |
| ▸ | MAPT | P10636 | 2/20 | 0.88 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.88 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.88 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.88 |
| ▸ | HPGD | P15428 | 1/20 | 0.88 |
| ▸ | MLNR | O43193 | 1/20 | 0.88 |
| ▸ | HTT | P42858 | 1/20 | 0.88 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.88 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.88 |
| ▸ | AR | P10275 | 3/20 | 0.70 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17519899 | 0.95 | LMNA (0.96) | NR3C1LMNAPGRCYP3A4SMN1; SMN2 | |
| Hydroxyprogesterone Caproate SCHEMBL16812894 | 0.94 | LMNA (1.00) | NR3C1LMNAPGRCYP3A4SMN1; SMN2 | |
| Hydroxyprogesterone Caproate SCHEMBL5330 | 0.94 | LMNA (1.00) | NR3C1LMNAPGRCYP3A4SMN1; SMN2 | |
| Hydroxyprogesterone Caproate SCHEMBL17517045 | 0.94 | LMNA (1.00) | NR3C1LMNAPGRCYP3A4SMN1; SMN2 | |
| Hydroxyprogesterone Caproate SCHEMBL14649335 | 0.94 | LMNA (1.00) | NR3C1LMNAPGRCYP3A4SMN1; SMN2 | |
| Hydroxyprogesterone Caproate SCHEMBL508890 | 0.94 | LMNA (1.00) | NR3C1LMNAPGRCYP3A4SMN1; SMN2 | |
| Hydroxyprogesterone Caproate SCHEMBL21497316 | 0.94 | LMNA (1.00) | NR3C1LMNAPGRCYP3A4SMN1; SMN2 | |
| Hydroxyprogesterone Caproate SCHEMBL94788 | 0.94 | LMNA (1.00) | NR3C1LMNAPGRCYP3A4SMN1; SMN2 | |
| SCHEMBL14656870 | 0.93 | LMNA (0.98) | NR3C1LMNAPGRCYP3A4SMN1; SMN2 | |
| SCHEMBL5425550 | 0.93 | LMNA (0.98) | NR3C1LMNAPGRCYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180117024-A1 | METHODS FOR INHIBITING PRETERM LABOR AND UTERINE CONTRACTILITY DISORDERS AND PREVENTING CERVICAL RIPENING | DIGNITY HEALTH | 2018-05-03 | — | — | US | disclosed |
| US-20180117024-A1 | METHODS FOR INHIBITING PRETERM LABOR AND UTERINE CONTRACTILITY DISORDERS AND PREVENTING CERVICAL RIPENING | DIGNITY HEALTH | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180117024-A1 | METHODS FOR INHIBITING PRETERM LABOR AND UTERINE CONTRACTILITY DISORDERS AND PREVENTING CERVICAL RIPENING | PGF, PTGS1, PTGIS | NR3C1 177/4885LMNA 55/4885PGR 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.