Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511426 | 1.00 | GAA (0.45) | GAASMN1; SMN2MAPK1KDM4EALDH1A1 | |
| SCHEMBL11513078 | 0.87 | HDAC2 (0.48) | GAASMN1; SMN2MAPK1ALDH1A1TSHR | |
| SCHEMBL17153776 | 0.79 | KDM4E (0.59) | GAASMN1; SMN2MAPK1KDM4EALDH1A1 | |
| SCHEMBL11512751 | 0.77 | RXRA (0.42) | GAASMN1; SMN2MAPK1KDM4EALDH1A1 | |
| SCHEMBL6264206 | 0.76 | KDM4E (0.56) | GAASMN1; SMN2MAPK1KDM4EALDH1A1 | |
| SCHEMBL11511349 | 0.76 | DRD2 (0.62) | GAASMN1; SMN2ALDH1A1TSHRKMT2A | |
| SCHEMBL11510781 | 0.75 | TSHR (0.47) | GAASMN1; SMN2ALDH1A1TSHRUSP2 | |
| SCHEMBL11511118 | 0.75 | NPC1 (0.37) | GAASMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL11512169 | 0.75 | CETP (0.49) | GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL11511382 | 0.74 | L3MBTL1 (0.37) | GAAMAPK1ALDH1A1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |