Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | HPGD | P15428 | 8/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.73 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA3 | P07451 | 2/20 | 0.65 |
| ▸ | CA4 | P22748 | 2/20 | 0.65 |
| ▸ | CA5A | P35218 | 2/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.65 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26804667 | 0.90 | NOD2 (0.79) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL30231784 | 0.88 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL12227473 | 0.88 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL14997043 | 0.88 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL2689251 | 0.85 | NOD2 (0.67) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL13691929 | 0.85 | NOD2 (0.67) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL31114282 | 0.85 | NOD2 (0.85) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| Hymecromone Methyl Ether SCHEMBL314248 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| Hymecromone Methyl Ether SCHEMBL31103478 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10CA12 | |
| SCHEMBL30803821 | 0.84 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259265-B2 | Coumarin compounds and method for preparing and using the same | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2007-08-21 | — | — | US | disclosed |
| US-7259265-B2 | Coumarin compounds and method for preparing and using the same | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2007-08-21 | — | — | US | disclosed |