Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561617 | 0.81 | TYMS (0.45) | KDM4EHSD17B10HPGDMAPTESR1 | |
| SCHEMBL29733364 | 0.80 | TYMS (0.44) | KDM4EHSD17B10HPGDMAPTESR1 | |
| SCHEMBL29733295 | 0.80 | TYMS (0.44) | KDM4EHSD17B10HPGDMAPTESR1 | |
| SCHEMBL29733319 | 0.80 | TYMS (0.44) | KDM4EHSD17B10HPGDMAPTESR1 | |
| SCHEMBL27722932 | 0.79 | TYMS (0.43) | KDM4EHSD17B10HPGDMAPTESR1 | |
| SCHEMBL2834574 | 0.79 | HSD17B10 (0.59) | KDM4EHSD17B10HPGDMAPTESR1 | |
| SCHEMBL11040570 | 0.79 | HSD17B10 (0.59) | KDM4EHSD17B10HPGDMAPTESR1 | |
| SCHEMBL10707682 | 0.79 | HSD17B10 (0.59) | KDM4EHSD17B10HPGDMAPTESR1 | |
| SCHEMBL29591103 | 0.79 | ALDH1A1 (0.50) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL19468524 | 0.79 | ALDH1A1 (0.50) | KDM4EHSD17B10HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162188-A | IN PRESENCE OF MALEIC ACID OR ITS SODIUM OR POTASSIUM SALT, MESACONIC ACID OR ITS SODIUM SALT, OR MALEIC ANHYDRIDE | HONSHU SEISHI KABUSHIKI KAISHA (JP) | 1979-07-24 | — | — | US | disclosed |