Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 4/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684548 | 0.81 | DRD2 (0.56) | DRD2DRD3DRD4 | |
| SCHEMBL7803709 | 0.75 | NPC1 (0.45) | DRD2DRD3DRD4 | |
| SCHEMBL7815804 | 0.75 | NPC1 (0.45) | DRD2DRD3DRD4 | |
| SCHEMBL6847027 | 0.72 | DRD2 (0.47) | DRD2DRD3DRD4MAPT | |
| SCHEMBL7304447 | 0.71 | DGAT1 (0.58) | ALDH1A1POLBMAPTTDP1DGAT1 | |
| SCHEMBL7292707 | 0.71 | DGAT1 (0.58) | ALDH1A1POLBMAPTTDP1DGAT1 | |
| SCHEMBL3406500 | 0.71 | DGAT1 (0.58) | ALDH1A1POLBMAPTTDP1DGAT1 | |
| SCHEMBL30612421 | 0.71 | DGAT1 (0.58) | ALDH1A1POLBMAPTTDP1DGAT1 | |
| Maleic Acid SCHEMBL8763115 | 0.71 | DRD2 (0.41) | DRD2DRD3DRD4ALDH1A1 | |
| SCHEMBL8683776 | 0.71 | DRD2 (0.49) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176196-A | Hypoglycemic arylcyclohexane acetic acids | PFIZER INC. (US) | 1979-11-27 | — | — | US | disclosed |