Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | AR | P10275 | 5/20 | 0.61 |
| ▸ | PGR | P06401 | 5/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152035 | 0.91 | LMNA (0.81) | LMNAMEN1KMT2ATDP1AR | |
| SCHEMBL11512435 | 0.81 | FNTA (0.73) | LMNAMEN1KMT2ATDP1AR | |
| Melengestrol Acetate SCHEMBL15079259 | 0.81 | LMNA (1.00) | LMNAMEN1KMT2ATDP1AR | |
| Melengestrol Acetate SCHEMBL4520 | 0.81 | LMNA (1.00) | LMNAMEN1KMT2ATDP1AR | |
| Melengestrol Acetate SCHEMBL10867312 | 0.81 | LMNA (1.00) | LMNAMEN1KMT2ATDP1AR | |
| Melengestrol Acetate SCHEMBL16389279 | 0.81 | LMNA (1.00) | LMNAMEN1KMT2ATDP1AR | |
| Melengestrol Acetate SCHEMBL13778228 | 0.81 | LMNA (1.00) | LMNAMEN1KMT2ATDP1AR | |
| Melengestrol Acetate SCHEMBL31477812 | 0.80 | LMNA (0.91) | LMNAMEN1KMT2ATDP1AR | |
| SCHEMBL8859712 | 0.80 | LMNA (0.78) | LMNAMEN1KMT2ATDP1AR | |
| SCHEMBL30291851 | 0.80 | LMNA (0.81) | LMNAMEN1KMT2ATDP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177269-A | ANTITUMOR AGENTS | AKTIEBOLAGET LEO (SE) | 1979-12-04 | — | — | US | disclosed |