Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | PGR | P06401 | 5/20 | 0.69 |
| ▸ | AR | P10275 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Melengestrol Acetate SCHEMBL16389279 | 1.00 | LMNA (1.00) | LMNAMEN1KMT2ATDP1PGR | |
| Melengestrol Acetate SCHEMBL13778228 | 1.00 | LMNA (1.00) | LMNAMEN1KMT2ATDP1PGR | |
| Melengestrol Acetate SCHEMBL10867312 | 1.00 | LMNA (1.00) | LMNAMEN1KMT2ATDP1PGR | |
| Melengestrol Acetate SCHEMBL4520 | 1.00 | LMNA (1.00) | LMNAMEN1KMT2ATDP1PGR | |
| Melengestrol Acetate SCHEMBL31477812 | 0.95 | LMNA (0.91) | LMNAMEN1KMT2ATDP1PGR | |
| SCHEMBL30152035 | 0.90 | LMNA (0.81) | LMNAMEN1KMT2ATDP1PGR | |
| SCHEMBL30291851 | 0.90 | LMNA (0.81) | LMNAMEN1KMT2ATDP1PGR | |
| SCHEMBL8859712 | 0.88 | LMNA (0.78) | LMNAMEN1KMT2ATDP1PGR | |
| SCHEMBL9992871 | 0.87 | LMNA (0.77) | LMNAMEN1KMT2ATDP1PGR | |
| SCHEMBL8859672 | 0.87 | LMNA (0.77) | LMNAMEN1KMT2ATDP1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296780-B2 | Process for alkynylating 16-substituted-17-keto steroids | CRYSTAL PHARMA, S.A.U. (ES) | 2016-03-29 | — | — | US | disclosed |
| EP-2794632-B1 | PROCESS FOR ALKYNYLATING 16-SUBSTITUTED-17-KETO STEROIDS | CRYSTAL PHARMA SAU (ES) | 2016-03-16 | — | — | EP | disclosed |
| US-20150005518-A1 | PROCESS FOR ALKYNYLATING 16-SUBSTITUTED-17-KETO STEROIDS | CRYSTAL PHARMA, S.A.U. (ES) | 2015-01-01 | — | — | US | disclosed |
| WO-2013092668-A1 | PROCESS FOR ALKYNYLATING 16-SUBSTITUTED-17-KETO STEROIDS | CRYSTAL PHARMA, S.A.U. (ES) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005518-A1 | PROCESS FOR ALKYNYLATING 16-SUBSTITUTED-17-KETO STEROIDS | HSD17B7, NR3C2, CYP17A1 | LMNA 553/4885MEN1 196/4885KMT2A 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.